MP-A08
MP-A08 is a potent and selective ATP-competitive inhibitor of sphingosine kinases, demonstrating higher affinity for SphK1 (Ki: 6.9 μM) than SphK2 (Ki: 27 μM) . This small molecule is a valuable research tool for investigating the sphingolipid signaling pathway in both cellular and animal models of cancer, inflammation, and other diseases.
Product Specifications
CAS Number
219832-49-2
Product Name Alternative
Inhibit, MPA08, MP-A08, MP-A-08, MP A08, Inhibitor, S1PReceptor, S1P Receptor, SphK, SphK1, Sphingosine kinase
Field of Research
Pharmacology & Drug Discovery
Purity
97.44% (May vary between batches)
Solubility
H2O:insoluble; DMSO:55 mg/mL (105.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.85 mM)
Smiles
Cc1ccc (cc1) S (=O) (=O) Nc1ccccc1\C=N\c1ccccc1NS (=O) (=O) c1ccc (C) cc1
Molecular Formula
C27H25N3O4S2
Molecular Weight
519.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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