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MA220607

MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA) . MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively) [1].

Product Specifications

CAS Number

2922826-56-8

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ma220607.html

Purity

97.11

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

C[N+]1=CC(C2=CC=CC=C2)=C(/C=C/C3=CC=C(C(C)(C)C)C=C3)C=C1C4=CC=C(C(C)(C)C)C=C4.[I-]

Molecular Formula

C34H38IN

Molecular Weight

587.58

References & Citations

[1]Ma Y et al. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes. Eur J Med Chem. 2023 Nov 7;263:115930.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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