NIK SMI1
NIK SMI1 is a potent and selective inhibitor of NF-κB inducing kinase (NIK), effectively blocking its ATPase activity with an IC50 of 0.23±0.17 nM. This small molecule is a valuable research tool for studying the non-canonical NF-κB pathway in both cellular and animal models of inflammation and oncology.
Product Specifications
CAS Number
1660114-31-7
Product Name Alternative
Inhibit, NIK, NIK SMI 1, NIK SMI1, NIK SMI-1, NFkB, NF-kB, NF-κB, NFκB, Nuclear factor-κB, Nuclear factor-kappaB, Inhibitor
Field of Research
Signal Transduction
Purity
99.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.95 mM) ; DMSO:100 mg/mL (273.69 mM)
Smiles
COc1cc (nc (c1) -c1cccc (c1) C#C[C@]1 (O) CCN (C) C1=O) C (N) =O
Molecular Formula
C20H19N3O4
Molecular Weight
365.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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