PQR530
PQR530 is a potent dual pan-PI3K/mTORC1/2 inhibitor, suppressing PKB (pSer473) and S6 (pSer235/236) phosphorylation with an IC50 of 0.07 μM. It demonstrates antitumor activity and is a valuable tool for investigating PI3K/mTOR signaling in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
1927857-61-1
Product Name Alternative
Phosphoinositide 3-kinase, PI3K, PQR 530, PQR530, PQR-530, Mammalian target of Rapamycin, Inhibitor, inhibit, mTORC1, mTORC2, mTOR
Field of Research
Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
DMSO:25 mg/mL (61.36 mM)
Smiles
C[C@H]1COCCN1c1nc (nc (n1) -c1cnc (N) cc1C (F) F) N1CCOCC1
Molecular Formula
C18H23F2N7O2
Molecular Weight
407.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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