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PQR530

PQR530 is a potent dual pan-PI3K/mTORC1/2 inhibitor, suppressing PKB (pSer473) and S6 (pSer235/236) phosphorylation with an IC50 of 0.07 μM. It demonstrates antitumor activity and is a valuable tool for investigating PI3K/mTOR signaling in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

1927857-61-1

Product Name Alternative

Phosphoinositide 3-kinase, PI3K, PQR 530, PQR530, PQR-530, Mammalian target of Rapamycin, Inhibitor, inhibit, mTORC1, mTORC2, mTOR

Field of Research

Signal Transduction

Purity

99.50% (May vary between batches)

Solubility

DMSO:25 mg/mL (61.36 mM)

Smiles

C[C@H]1COCCN1c1nc (nc (n1) -c1cnc (N) cc1C (F) F) N1CCOCC1

Molecular Formula

C18H23F2N7O2

Molecular Weight

407.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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