JW74
JW74 is a potent small molecule inhibitor of canonical Wnt signaling, exhibiting an IC50 of 420 nM against LiCl-induced pathway activation. This tool compound is valuable for in vitro and in vivo research investigating Wnt/β-catenin signaling in development, oncology, and stem cell biology.
Product Specifications
CAS Number
863405-60-1
Product Name Alternative
Wnt, Wnt/b-catenin, Wnt/β-catenin, Wnt/betacatenin, βcatenin, JW 74, JW74, JW-74, inhibit, Inhibitor, bcatenin, beta-catenin, betacatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
95.00% (May vary between batches)
Solubility
DMSO:45 mg/mL (98.57 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM)
Smiles
COc1ccc (cc1) -n1c (SCc2nc (no2) -c2ccc (C) cc2) nnc1-c1ccncc1
Molecular Formula
C24H20N6O2S
Molecular Weight
456.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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