Ancitabine hydrochloride
Ancitabine hydrochloride is a prodrug of cytarabine that undergoes slow hydrolysis to release the active antimetabolite. Its conversion provides sustained cytarabine levels, leading to S-phase-specific termination of DNA replication and inhibition of DNA polymerase, which is utilized in oncology research for studying leukemia and solid tumor models both in vitro and in vivo.
Product Specifications
CAS Number
10212-25-6
Product Name Alternative
NSC 145668 HCl, Ancitabine, Autophagy, CMV, DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, Cyclo-C, Cyclo-C HCl, Cyclo-CMP, Cyclo-CMP hydrochloride, Cyclocytidine, Cyclocytidine HCl, Cyclocytidine hydrochloride, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.02% (May vary between batches)
Solubility
H2O:26.31 mg/mL (100.55 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.82 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:10 mg/mL (38.22 mM)
Smiles
Cl.[C@@H]12[C@@H] (Oc3n1ccc (=N) n3) [C@@H] ([C@H] (O2) CO) O
Molecular Formula
C9H12ClN3O4
Molecular Weight
261.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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