Isavuconazole
Isavuconazole (BAL-4815) is the active moiety of the prodrug isavuconazonium sulfate (BAL8557), a broad-spectrum triazole antifungal. It demonstrates potent in vitro activity against Candida species, with MIC values ranging from ≤0.004 mg/L for C. albicans to 0.5 mg/L for C. glabrata. This agent is widely used in research models to study invasive fungal infections and antifungal efficacy.
Product Specifications
CAS Number
241479-67-4
Product Name Alternative
Inhibitor, Fungal, fungi, ergosterol, Isavuconazole, inhibit, molds, dimorphic, CYPs, Cytochrome P450, Antibiotic, Antifungal, BAL 4815, BAL4815, BAL-4815, biosynthesis, triazole, RO0094815, RO-0094815, RO 0094815, yeasts, prodrug
Field of Research
Infectious Disease & Virology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.57 mM) ; DMSO:250 mg/mL (571.47 mM)
Smiles
[C@@] ([C@@H] (C) C1=NC (=CS1) C2=CC=C (C#N) C=C2) (CN3C=NC=N3) (O) C4=C (F) C=CC (F) =C4
Molecular Formula
C22H17F2N5OS
Molecular Weight
437.47
Storage Conditions
-20°C
Notes
For research use only.
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