SB 218795
SB 218795 is a potent and selective neurokinin 3 (NK3) receptor antagonist, exhibiting a Ki of 13 nM for hNK3 with 90-fold and 7000-fold selectivity over hNK2 and hNK1, respectively. This compound is a valuable research tool for investigating the role of NK3 in central nervous system functions and reproductive physiology in both in vitro and in vivo studies.
Product Specifications
CAS Number
174635-53-1
Product Name Alternative
Constriction, Inhibitor, inhibit, NK3, NK-3, NK receptor, Neurokininreceptor, neurokinin-3, Neurokinin receptor, Neurokinin Receptor, Tachykinin receptor, SB218795, SB-218795, SB 218795, pupillary
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.70% (May vary between batches)
Solubility
DMSO:60 mg/mL (151.35 mM) ; Ethanol:5 mM
Smiles
C (N[C@@H] (C (OC) =O) C1=CC=CC=C1) (=O) C=2C3=C (N=C (C2) C4=CC=CC=C4) C=CC=C3
Molecular Formula
C25H20N2O3
Molecular Weight
396.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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