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RVX-208

Apabetalone (RVX-000222) is a selective BET bromodomain inhibitor investigated for cardiovascular and metabolic diseases. Research demonstrates its potential in preclinical models of atherosclerosis and diabetes, showing modulation of key inflammatory and fibrotic pathways in both in vitro and in vivo studies.

Product Specifications

CAS Number

1044870-39-4

Product Name Alternative

RVX 000222, RVX 208, RVX000222, RVX-000222, RVX208, RVX-208, BD2, Apabetalone, EpigeneticReaderDomain, Epigenetic Reader Domain, HIVProtease, HIV, HIV Protease, Human immunodeficiency virus, inhibit, Inhibitor

Field of Research

Epigenetics & Chromatin

Purity

>98%

Bioactivity

BET bromodomain inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml) .

Smiles

COc1cc (OC) c2c (c1) [nH]c (nc2=O) -c1cc (C) c (OCCO) c (C) c1

Molecular Formula

C20H22N2O5

Molecular Weight

370.41

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2-[4- (2-hydroxyethoxy) -3,5-dimethylphenyl]-5,7-dimethoxy-4 (3H) -quinzolinone

Available Sizes

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