IOWH-032
IOWH-032 is a synthetic small molecule inhibitor of the CFTR chloride channel. It has been investigated in preclinical research for the treatment of secretory diarrheal diseases, including cholera, with studies demonstrating its efficacy in both in vitro assays and in vivo animal models of fluid secretion.
Product Specifications
CAS Number
1191252-49-9
Product Name Alternative
SARS coronavirus, SARS-CoV, anti-diarrheal, Autophagy, ACE-2, Cystic fibrosis transmembrane conductance regulator, CFBE41o- WT cells, CFTR, IOWH 032, IOWH032, IOWH-032, inhibit, Inhibitor
Field of Research
Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
DMSO:93 mg/mL (170.59 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.05 mM)
Smiles
Oc1c (Br) cc (cc1Br) -c1noc (n1) C (=O) NCc1ccc (Oc2ccccc2) cc1
Molecular Formula
C22H15Br2N3O4
Molecular Weight
545.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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