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IOWH-032

IOWH-032 is a synthetic small molecule inhibitor of the CFTR chloride channel. It has been investigated in preclinical research for the treatment of secretory diarrheal diseases, including cholera, with studies demonstrating its efficacy in both in vitro assays and in vivo animal models of fluid secretion.

Product Specifications

CAS Number

1191252-49-9

Product Name Alternative

SARS coronavirus, SARS-CoV, anti-diarrheal, Autophagy, ACE-2, Cystic fibrosis transmembrane conductance regulator, CFBE41o- WT cells, CFTR, IOWH 032, IOWH032, IOWH-032, inhibit, Inhibitor

Field of Research

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

≥95% (May vary between batches)

Solubility

DMSO:93 mg/mL (170.59 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.05 mM)

Smiles

Oc1c (Br) cc (cc1Br) -c1noc (n1) C (=O) NCc1ccc (Oc2ccccc2) cc1

Molecular Formula

C22H15Br2N3O4

Molecular Weight

545.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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