AM095
AM095 is a potent and selective antagonist of the lysophosphatidic acid receptor 1 (LPA1), demonstrating IC50 values of 0.98 μM for human and 0.73 μM for mouse recombinant receptors. This small molecule is a valuable research tool for investigating LPA1-mediated pathways in fibrosis, neuropathic pain, and cancer metastasis in both cellular and animal models.
Product Specifications
CAS Number
1345614-59-6
Product Name Alternative
AM 095, AM095, AM-095, Inhibitor, LPAReceptor, LPL, LPL Receptor, LPLReceptor, LPA Receptor, LPA1, Lysophospholipid Receptor, inhibit
Field of Research
Pharmacology & Drug Discovery
Purity
98.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.09 mM) ; DMSO:5.5 mg/mL (11.49 mM)
Smiles
[Na+].C[C@@H] (OC (=O) Nc1c (C) noc1-c1ccc (cc1) -c1ccc (CC ([O-]) =O) cc1) c1ccccc1
Molecular Formula
C27H23N2NaO5
Molecular Weight
478.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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