DMOG
DMOG (Dimethyloxalylglycine) is a cell-permeable competitive antagonist of α-ketoglutarate that inhibits HIF prolyl hydroxylase (HIF-PH), leading to HIF-1α stabilization. This action induces autophagy and promotes angiogenesis, making it a valuable tool for studying hypoxia pathways, ischemic disease models, and angiogenesis in both cellular and animal research.
Product Specifications
CAS Number
89464-63-1
Product Name Alternative
Dimethyloxalylglycine
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Bioactivity
Prolyl hydroxylase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
COC (=O) CNC (=O) C (=O) OC
Molecular Formula
C6H9NO5
Molecular Weight
175.14
Storage Conditions
-20°C / protect from light
Notes
For research use only.
Other Product Names
N- (2-Methoxy-2-oxoacetyl) glycine methyl ester
Available Sizes
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