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GNE-7915

GNE-7915 is a potent and selective small molecule inhibitor of LRRK2 kinase with demonstrated brain penetration. It is a valuable research tool for investigating LRRK2's role in Parkinson's disease pathogenesis, enabling both in vitro biochemical assays and in vivo preclinical studies in animal models.

Product Specifications

CAS Number

1351761-44-8

Product Name Alternative

Leucine-rich repeat kinase 2, Inhibitor, GNE-7915, GNE7915, GNE 7915, LRRK2, inhibit

Field of Research

Cell Biology

Purity

≥95% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM) ; DMSO:16.67 mg/mL (37.6 mM)

Smiles

CCNc1nc (Nc2cc (F) c (cc2OC) C (=O) N2CCOCC2) ncc1C (F) (F) F

Molecular Formula

C19H21F4N5O3

Molecular Weight

443.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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