GNE-7915
GNE-7915 is a potent and selective small molecule inhibitor of LRRK2 kinase with demonstrated brain penetration. It is a valuable research tool for investigating LRRK2's role in Parkinson's disease pathogenesis, enabling both in vitro biochemical assays and in vivo preclinical studies in animal models.
Product Specifications
CAS Number
1351761-44-8
Product Name Alternative
Leucine-rich repeat kinase 2, Inhibitor, GNE-7915, GNE7915, GNE 7915, LRRK2, inhibit
Field of Research
Cell Biology
Purity
≥95% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM) ; DMSO:16.67 mg/mL (37.6 mM)
Smiles
CCNc1nc (Nc2cc (F) c (cc2OC) C (=O) N2CCOCC2) ncc1C (F) (F) F
Molecular Formula
C19H21F4N5O3
Molecular Weight
443.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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