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Capmatinib

Capmatinib (INCB28060) is a selective, orally administered c-MET (HGFR) tyrosine kinase inhibitor. It is widely used in preclinical research, including in vitro cell-based assays and in vivo xenograft models, to investigate targeted therapies for cancers with MET dysregulation, such as non-small cell lung cancer.

Product Specifications

CAS Number

1029712-80-8

Product Name Alternative

U-87MG, orally active, SNU-5, S114, c-Met/HGFR, cMet/HGFR, c-Met, cMet, Capmatinib, Balb/c nu/nu mice, ATP competitive, Apoptosis, NVP-INC 280, NVP-INC280, NVP-INC-280, inhibit, INC 280, INC280, INC-280, INCB 28060, INCB28060, INCB-28060, HGFR, Inhibitor, H441

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.94% (May vary between batches)

Solubility

DMSO:4.13 mg/mL (10.01 mM)

Smiles

CNC (=O) c1ccc (cc1F) -c1cnc2ncc (Cc3ccc4ncccc4c3) n2n1

Molecular Formula

C23H17FN6O

Molecular Weight

412.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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