Gαq/11 protein-IN-1

Gαq/11 protein-IN-1 (compound F33) is an inhibitor of Gαq/11 protein with an IC50 value of 9.4 μM. Gαq/11 protein-IN-1 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Trace Amine-associated Receptor (TAAR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gαq-11-protein-in-1.html

Solubility

10 mM in DMSO

Smiles

C12=CC=CC=C1C(NC3CCCCC3)=NC(NC4CCNCC4)=N2

Molecular Formula

C19H27N5

Molecular Weight

325.45

References & Citations

[1]Guangjin Fan, et al .Design, synthesis and evaluation of quinazoline derivatives as Gαq/11 proteins inhibitors against uveal melanoma. Bioorg Chem. 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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