Idelalisib
Idelalisib is a potent and selective small molecule inhibitor of the PI3K p110δ isoform, demonstrating 40- to 300-fold selectivity over other PI3K class I isoforms. It is widely used in biochemical and cellular research to investigate B-cell malignancies and immune cell signaling, with applications in both in vitro and in vivo models of hematologic cancers.
Product Specifications
CAS Number
870281-82-6
Product Name Alternative
PI3K, Phosphoinositide 3-kinase, Inhibitor, GS 1101, GS1101, GS-1101, Idelalisib, inhibit, p110δ, p110γ, Autophagy, CAL 101, CAL101, CAL-101
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Ethanol:22 mg/mL (52.96 mM) ; H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM) ; DMSO:250 mg/mL (601.8 mM)
Smiles
[C@H] (NC1=C2C (N=CN2) =NC=N1) (CC) C=3N (C (=O) C=4C (N3) =CC=CC4F) C5=CC=CC=C5
Molecular Formula
C22H18FN7O
Molecular Weight
415.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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