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I-BET762

Molibresib (GSK525762) is a potent and selective BET bromodomain inhibitor with an IC50 of approximately 35 nM. It is widely used in cancer research, demonstrating activity in both in vitro assays and in vivo models for studying oncology and transcriptional regulation.

Product Specifications

CAS Number

1260907-17-2

Product Name Alternative

GSK525762

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation

Purity

>98%

Bioactivity

BET Bromodomain inhibitor; Suppresses Myc transcription

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)

Smiles

CCNC (=O) C[C@@H]1N=C (c2ccc (Cl) cc2) c2cc (OC) ccc2-n2c (C) nnc12

Molecular Formula

C22H22ClN5O2

Molecular Weight

423.90

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(4S) - 6- (4-Chlorophenyl) -N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide

Available Sizes

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