JSH-23
JSH-23 is a cell-permeable inhibitor that selectively blocks NF-κB-dependent transcriptional activity (IC50=7.1 μM) without preventing IκBα degradation. This antioxidant compound is used in vitro and in vivo to study inflammatory signaling pathways and oxidative stress-related mechanisms.
Product Specifications
CAS Number
749886-87-1
Product Name Alternative
Inhibitor, JSH 23, JSH23, JSH-23, inhibit, NF-κB, NFκB, NFkB, NF-kB, Nuclear factor-κB, Nuclear factor-kappaB
Field of Research
Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.8 mM) ; Ethanol:16 mg/mL (66.57 mM) ; DMSO:255 mg/mL (1061 mM)
Smiles
Cc1ccc (NCCCc2ccccc2) c (N) c1
Molecular Formula
C16H20N2
Molecular Weight
240.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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