5-fluoro 203
5-Fluoro-203 (NSC-703786) is a cytotoxic agent that forms DNA adducts, inducing cell death. It activates the aryl hydrocarbon receptor, upregulating CYP1A1, and triggers oxidative stress alongside p38, JNK, and ERK MAPK pathway activation. This compound is utilized in cancer research for studying DNA damage and AhR signaling in cellular models.
Product Specifications
CAS Number
260443-89-8
Product Name Alternative
NSC703786, NSC-703786, NSC 703786, inhibit, Inhibitor, 5fluoro 203, 5-fluoro 203, 5F 203, 5F203, 5F-203, 5 fluoro 203, AhR, Aryl Hydrocarbon Receptor
Field of Research
Immunology & Inflammation
Purity
97.61% (May vary between batches)
Solubility
DMSO:25 mg/mL (96.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.74 mM)
Smiles
Cc1cc (ccc1N) -c1nc2cc (F) ccc2s1
Molecular Formula
C14H11FN2S
Molecular Weight
258.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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