UNC 669
UNC 669 is a potent and selective small-molecule inhibitor of the MBT domain proteins L3MBTL1 and L3MBTL3, exhibiting IC50 values of 4.2 μM and 3.1 μM, respectively. This chemical probe is used in vitro to study chromatin regulation and transcriptional repression in cancer research, particularly for investigating malignant brain tumor (MBT) family function.
Product Specifications
CAS Number
1314241-44-5
Product Name Alternative
L3MBTL3, L3MBTL4, L3MBTL1, MBT, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, Inhibitor, transcriptional, repression, repeats, UNC669, UNC-669, UNC 669
Field of Research
Epigenetics & Chromatin
Purity
97.38% (May vary between batches)
Solubility
DMSO:9 mg/mL (26.61 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.96 mM) ; Ethanol:63 mg/mL (186.26 mM)
Smiles
Brc1cncc (c1) C (=O) N1CCC (CC1) N1CCCC1
Molecular Formula
C15H20BrN3O
Molecular Weight
338.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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