SBE13 Hydrochloride
SBE13 Hydrochloride is a potent and selective PLK1 inhibitor with an IC50 of 0.2 nM, demonstrating no activity against Aurora A or Plk2/3 kinases. It is a valuable chemical probe for studying mitosis and has been utilized in both in vitro and in vivo cancer research models to investigate targeted therapeutic strategies.
Product Specifications
CAS Number
1052532-15-6
Product Name Alternative
Autophagy, Apoptosis, inhibit, Inhibitor, PLK2, PLK3, PLK, PLK1, SBE 13, SBE 13 HCl, SBE 13 hydrochloride, SBE 13 Hydrochloride, SBE13, SBE-13, SBE13 Hydrochloride, SBE-13 Hydrochloride, Polo-like Kinase (PLK)
Field of Research
Cell Biology
Purity
≥95% (May vary between batches)
Solubility
DMSO:80 mg/mL (166.88 mM) ; H2O:4.8 mg/mL (10.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.88 mM)
Smiles
Clc1ncc (COc2c (OC) cc (CNCCc3cc (OC) c (OC) cc3) cc2) cc1.Cl
Molecular Formula
C24H28Cl2N2O4
Molecular Weight
479.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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