ML277
ML277 (CID-53347902) is a potent and selective small molecule activator of KCNQ1 potassium channels, exhibiting an EC50 of 260 nM. This compound is a valuable research tool for investigating channel function in cardiovascular and metabolic diseases, supporting both in vitro electrophysiology studies and in vivo physiological research.
Product Specifications
CAS Number
1401242-74-7
Product Name Alternative
(R) -N- (4- (4-Methoxyphenyl) thiazol-2-yl) -1-tosylpiperidine-2-carboxamide
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
COc1ccc (cc1) -c1csc (NC (=O) [C@H]2CCCCN2S (=O) (=O) c2ccc (C) cc2) n1
Molecular Formula
C23H25N3O4S2
Molecular Weight
471.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2R) -N-[4- (4-Methoxyphenyl) -2-thiazolyl]-1-[ (4-methylphenyl) (sulfonyl]-2-piperidinecarboxamide
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