Posaconazole
Posaconazole is a potent small molecule inhibitor of sterol 14α-demethylase, exhibiting an IC50 of 0.25 nM. This antifungal agent is widely used in research to study fungal pathogenesis and treatment, with applications in both in vitro assays and in vivo animal models of infection.
Product Specifications
CAS Number
171228-49-2
Product Name Alternative
POS, Posaconazole, SCH 56592, SCH56592, SCH-56592, inhibit, Inhibitor, Fungal, Antifungal
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.00% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:245 mg/mL (349.61 mM)
Smiles
C ([C@@]1 (C[C@H] (COC2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) N5C (=O) N ([C@H] ([C@H] (C) O) CC) N=C5) CO1) C6=C (F) C=C (F) C=C6) N7C=NC=N7
Molecular Formula
C37H42F2N8O4
Molecular Weight
700.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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