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AZ191

AZ191 is a potent and selective DYRK1B inhibitor with an IC50 of 17 nM, exhibiting approximately 5-fold and 110-fold selectivity over DYRK1A and DYRK2, respectively. This small molecule is a valuable research tool for studying DYRK1B's role in cellular signaling, proliferation, and metabolic pathways in both in vitro and in vivo models.

Product Specifications

CAS Number

1594092-37-1

Product Name Alternative

AZ 191, AZ191, AZ-191, DYRK, DYRK1A, DYRK1B, DYRK2, Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, inhibit, Inhibitor

Field of Research

Cell Biology, Signal Transduction

Purity

98.04% (May vary between batches)

Solubility

Ethanol:1 mg/mL (2.33 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM) ; DMSO:79 mg/mL (183.93 mM)

Smiles

COc1cc (ccc1Nc1nccc (n1) -c1cn (C) c2cnccc12) N1CCN (C) CC1

Molecular Formula

C24H27N7O

Molecular Weight

429.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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