AZ191
AZ191 is a potent and selective DYRK1B inhibitor with an IC50 of 17 nM, exhibiting approximately 5-fold and 110-fold selectivity over DYRK1A and DYRK2, respectively. This small molecule is a valuable research tool for studying DYRK1B's role in cellular signaling, proliferation, and metabolic pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
1594092-37-1
Product Name Alternative
AZ 191, AZ191, AZ-191, DYRK, DYRK1A, DYRK1B, DYRK2, Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, inhibit, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
98.04% (May vary between batches)
Solubility
Ethanol:1 mg/mL (2.33 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM) ; DMSO:79 mg/mL (183.93 mM)
Smiles
COc1cc (ccc1Nc1nccc (n1) -c1cn (C) c2cnccc12) N1CCN (C) CC1
Molecular Formula
C24H27N7O
Molecular Weight
429.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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