PF04929113
PF04929113 (SNX-5422) is an orally bioavailable, small-molecule inhibitor of Hsp90. It has demonstrated potent anti-tumor activity in preclinical studies, showing efficacy in both in vitro assays and in vivo xenograft models across various cancer types, including breast and lung cancers.
Product Specifications
CAS Number
908115-27-5
Product Name Alternative
PF 04929113, PF04929113, PF-04929113, SNX 5422, SNX5422, SNX-5422, HSP90, HER2
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Purity
99.04% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:3 mg/mL (5.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.79 mM) ; DMSO:96 mg/mL (184.07 mM)
Smiles
C (F) (F) (F) C=1C2=C (N (N1) C3=CC (N[C@@H]4CC[C@@H] (OC (CN) =O) CC4) =C (C (N) =O) C=C3) CC (C) (C) CC2=O
Molecular Formula
C25H30F3N5O4
Molecular Weight
521.53
Storage Conditions
-20°C
Notes
For research use only.
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