AS-604850
AS-604850 is a potent and selective ATP-competitive inhibitor of PI3Kγ, exhibiting an IC50 of 250 nM. It shows 18-fold selectivity over PI3Kα and >80-fold selectivity over PI3Kδ/β. This inhibitor is a valuable research tool for studying PI3Kγ's role in inflammation and immune cell signaling in both cellular and animal models.
Product Specifications
CAS Number
648449-76-7
Product Name Alternative
Inhibit, Inhibitor, AS 604850, AS604850, AS-604850, Phosphoinositide 3-kinase, PI3Kα, PI3K, PI3Kβ, PI3Kγ, PI3Kδ
Field of Research
Signal Transduction
Purity
99.65% (May vary between batches)
Solubility
Ethanol:5 mg/mL (17.53 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.01 mM) ; DMSO:57 mg/mL (199.85 mM)
Smiles
FC1 (F) Oc2ccc (\C=C3/SC (=O) NC3=O) cc2O1
Molecular Formula
C11H5F2NO4S
Molecular Weight
285.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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