TTBK1-IN-2
TTBK1-IN-2 is a potent small molecule inhibitor of Tau-Tubulin Kinase 1 (TTBK1), exhibiting IC50 values of 0.24 μM and 4.22 μM. It effectively reduces pathological TDP-43 phosphorylation in both cellular models and in vivo, as demonstrated in transgenic mouse spinal cords, making it a valuable research tool for neurodegenerative disease studies.
Product Specifications
CAS Number
2765453-51-6
Product Name Alternative
N-[4- (4-chlorophenoxy) phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Microtubule Associated, MicrotubuleAssociated, tau, TTBK1-IN-2, Tubulin
Field of Research
Neuroscience, Signal Transduction
Purity
99.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.94 mM) ; DMSO:55 mg/mL (163.32 mM)
Smiles
Clc1ccc (Oc2ccc (Nc3ncnc4[nH]ccc34) cc2) cc1
Molecular Formula
C18H13ClN4O
Molecular Weight
336.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal SRP72 Antibody [Alexa Fluor 350]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
Rabbit Polyclonal SRP72 Antibody [Alexa Fluor 350]
