PLN-1474
PLN-1474 is a highly potent and selective small molecule inhibitor of the integrin αVβ1, exhibiting an IC50 of less than 50 nM. This compound is a valuable research tool for studying fibrotic pathways and has demonstrated efficacy in reducing fibrosis in both cellular assays and preclinical in vivo models of liver and lung disease.
Product Specifications
CAS Number
2408065-32-5
Product Name Alternative
PLN 1474, PLN1474, PLN-1474, αVβ1 integrin
Field of Research
Cell Biology, Signal Transduction
Purity
99.25% (May vary between batches)
Solubility
DMSO:50 mg/mL (115.86 mM)
Smiles
CC1 (CCOCC1) C (=O) N[C@@H] (CCCCCCCC1=CC=C2CCCN=C2N1) C (O) =O
Molecular Formula
C24H37N3O4
Molecular Weight
431.57
Storage Conditions
-20°C
Notes
For research use only.
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