Maraviroc
Maraviroc is a selective CCR5 antagonist that potently inhibits the binding of chemokines MIP-1α, MIP-1β, and RANTES. It blocks HIV-1 entry via CCR5 and is widely used in virology research for studying viral entry mechanisms, coreceptor tropism, and in antiviral assays both in vitro and in vivo.
Product Specifications
CAS Number
376348-65-1
Product Name Alternative
UK-427,857
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
CCR5 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
CC (C) c1nnc (C) n1[C@@H]1C[C@@H]2CC[C@H] (C1) N2CC[C@H] (NC (=O) C1CCC (F) (F) CC1) c1ccccc1
Molecular Formula
C29H41F2N5O
Molecular Weight
513.7
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4,4-difluoro-N-[ (1S) -3-[ (1R,5S) -3- (3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl) -8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
Available Sizes
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