SCH772984
SCH772984 is a potent, selective, and ATP-competitive ERK1/2 inhibitor (IC50=4/1 nM) . It demonstrates antitumor efficacy in both in vitro and in vivo models of cancers harboring BRAF or RAS mutations, making it a valuable tool for MAPK pathway research.
Product Specifications
CAS Number
942183-80-4
Product Name Alternative
Inhibit, Extracellular signal regulated kinases, ERK2, ERK, ERK1, Inhibitor, SCH772984, SCH-772984, SCH 772984
Field of Research
Signal Transduction
Purity
95.53% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Saline:0.54 mg/mL (0.92 mM) ; DMSO:16.7 mg/mL (28.42 mM)
Smiles
O=C (CN1CC[C@H] (C1) C (=O) Nc1ccc2[nH]nc (-c3ccncc3) c2c1) N1CCN (CC1) c1ccc (cc1) -c1ncccn1
Molecular Formula
C33H33N9O2
Molecular Weight
587.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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