Tivantinib
Tivantinib (ARQ 197) is an orally administered small molecule that selectively inhibits the c-Met receptor tyrosine kinase. It has demonstrated antineoplastic activity in preclinical studies, showing efficacy in both in vitro cell proliferation assays and in vivo xenograft models of various cancers, including hepatocellular and non-small cell lung carcinomas.
Product Specifications
CAS Number
905854-02-6
Product Name Alternative
C-Met/HGFR, cMet, c-Met, cMet/HGFR, Apoptosis, ARQ 197, ARQ197, ARQ-197, HGFR, Inhibitor, inhibit, Tivantinib
Field of Research
Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.41 mM) ; DMSO:125 mg/mL (338.37 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C1NC (=O) [C@H] ([C@@H]1c1c[nH]c2ccccc12) c1cn2CCCc3cccc1c23
Molecular Formula
C23H19N3O2
Molecular Weight
369.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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