Tirofiban
Tirofiban (L700462, MK-383) is a potent and selective antagonist of the platelet GPIIb/IIIa receptor, inhibiting aggregation with an IC50 of 9 nM. It is widely used in cardiovascular research to study thrombosis and has been applied in both in vitro platelet function assays and in vivo models of arterial injury.
Product Specifications
CAS Number
144494-65-5
Product Name Alternative
Antithrombotic, AMI, Aggrastat, ACSs, Integrin, Inhibitor, HUVEC, L700462, L-700462, GPIIb/IIIa, HAEC, inhibit, L 700462, MK 383, MK383, MK-383, Tirofiban, VEGF
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.83% (May vary between batches)
Solubility
1M HCL:54 mg/mL (122.56 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCCCS (=O) (=O) N[C@@H] (Cc1ccc (OCCCCC2CCNCC2) cc1) C (O) =O
Molecular Formula
C22H36N2O5S
Molecular Weight
440.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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