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Aristolochic acid (A&B)

Aristolochic acid A, a primary component in Aristolochia and Asarum extracts, potently inhibits AP-1 and NF-κB activity while downregulating the BLCAP gene. It is widely utilized in research to establish nephrotoxicity models in vivo and to study its effects on cancer-related pathways in vitro.

Product Specifications

CAS Number

313-67-7

Product Name Alternative

Mixture of Aristolochic Acid A and B

Field of Research

Cell Biology

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 30 mg/ml)

Smiles

COc1cccc2c1cc ([N+] ([O-]) =O) c1c (cc3OCOc3c21) C (O) =O

Molecular Formula

C17H11NO7 and C16H9NO6

Molecular Weight

341.3 and 311.3

Storage Conditions

RT

Notes

For research use only.

Other Product Names

8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (A) and 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (B)

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