Aristolochic acid (A&B)
Aristolochic acid A, a primary component in Aristolochia and Asarum extracts, potently inhibits AP-1 and NF-κB activity while downregulating the BLCAP gene. It is widely utilized in research to establish nephrotoxicity models in vivo and to study its effects on cancer-related pathways in vitro.
Product Specifications
CAS Number
313-67-7
Product Name Alternative
Mixture of Aristolochic Acid A and B
Field of Research
Cell Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml)
Smiles
COc1cccc2c1cc ([N+] ([O-]) =O) c1c (cc3OCOc3c21) C (O) =O
Molecular Formula
C17H11NO7 and C16H9NO6
Molecular Weight
341.3 and 311.3
Storage Conditions
RT
Notes
For research use only.
Other Product Names
8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (A) and 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (B)
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