CGP77675
CGP77675 (ZINC1488120) is a potent, selective Src family kinase inhibitor, demonstrating IC50 values of 5-20 nM for peptide substrate phosphorylation and 40 nM for Src autophosphorylation. Its anticancer activity supports its use in vitro and in vivo for researching cancer cell signaling, proliferation, and metastasis.
Product Specifications
CAS Number
234772-64-6
Product Name Alternative
ZINC 1488120, ZINC1488120, ZINC-1488120, Src, v-Abl, EGFR, Lck, KDR, BcrAbl, 1- (4- (4-amino-5- (3-methoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-7-yl) phenethyl) piperidin-4-ol, CGP77675, CGP-77675, CGP 77675
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.23% (May vary between batches)
Solubility
DMSO:55 mg/mL (124 mM) ;10% DMSO+90% Saline:2.5 mg/mL (5.64 mM)
Smiles
NC1=C2C (=CN (C2=NC=N1) C3=CC=C (CCN4CCC (O) CC4) C=C3) C5=CC (OC) =CC=C5
Molecular Formula
C26H29N5O2
Molecular Weight
443.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15298297 1 Vial
Lentiviral mouse Rhox3h shRNA (UAS) - Lentiviral mouse Rhox3h shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details 
010418 500 mg
2,2-Dimethyl-1,3-dioxane-5,5-dicarboxylic Acid Dimethyl Ester
Sign In for Pricing
View Details 