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NS1643

NS1643 is a small molecule activator of the hERG (KV11.1) potassium channel, exhibiting an EC50 of 10.5 μM. It is a valuable research tool for studying cardiac electrophysiology, Long QT Syndrome, and arrhythmia mechanisms in both cellular and tissue-based experimental models.

Product Specifications

CAS Number

448895-37-2

Product Name Alternative

PotassiumChannel, Potassium Channel, inhibit, KcsA, NS1643, NS-1643, NS 1643, hERG, Inhibitor, Autophagy

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.37% (May vary between batches)

Solubility

Ethanol:100 mM; DMSO:50 mg/mL (131.5 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM)

Smiles

Oc1ccc (cc1NC (=O) Nc1cc (ccc1O) C (F) (F) F) C (F) (F) F

Molecular Formula

C15H10F6N2O3

Molecular Weight

380.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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