NS1643
NS1643 is a small molecule activator of the hERG (KV11.1) potassium channel, exhibiting an EC50 of 10.5 μM. It is a valuable research tool for studying cardiac electrophysiology, Long QT Syndrome, and arrhythmia mechanisms in both cellular and tissue-based experimental models.
Product Specifications
CAS Number
448895-37-2
Product Name Alternative
PotassiumChannel, Potassium Channel, inhibit, KcsA, NS1643, NS-1643, NS 1643, hERG, Inhibitor, Autophagy
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.37% (May vary between batches)
Solubility
Ethanol:100 mM; DMSO:50 mg/mL (131.5 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM)
Smiles
Oc1ccc (cc1NC (=O) Nc1cc (ccc1O) C (F) (F) F) C (F) (F) F
Molecular Formula
C15H10F6N2O3
Molecular Weight
380.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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