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Astragaloside IV

Astragaloside IV is a bioactive saponin from Astragalus membranaceus with broad research applications. It exhibits anti-cancer activity in vitro by inhibiting ERK/JNK signaling and MMPs in MDA-MB-231 cells, and demonstrates cardioprotective effects in vivo, reducing infarct size in canine models. It also shows antiviral activity against HAdV-3 replication in A549 cells.

Product Specifications

CAS Number

84687-43-4

Product Name Alternative

AS-IV, Astragaloside IV, AST-IV, Matrix metalloproteinases, ERS, ERK, Extracellular signal regulated kinases, Estrogen Receptor, EstrogenReceptor, MMP, Inhibitor, inhibit, JNK, progestogen Receptor, progestogenReceptor

Field of Research

Metabolism Research, Protein Biochemistry, Signal Transduction

Purity

98.85% (May vary between batches)

Solubility

DMSO:100 mg/mL (127.39 mM)

Smiles

CC (C) (O) [C@@H]1CC[C@@] (C) (O1) [C@H]1[C@H] (O) C[C@@]2 (C) C3C[C@@H] (O[C@@H]4O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]4O) C4[C@]5 (CC35CC[C@]12C) CCC (O[C@@H]1OC[C@@H] (O) [C@H] (O) [C@H]1O) C4 (C) C

Molecular Formula

C41H68O14

Molecular Weight

784.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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