Ponicidin
Ponicidin (Rubescensine B) is a bioactive diterpenoid isolated from Rabdosia rubescens. It demonstrates immunoregulatory, anti-inflammatory, antiviral, and anticancer properties, such as inducing apoptosis in gastric carcinoma cells by inhibiting JAK2/STAT3 phosphorylation. Research applications include in vitro studies on cancer cell lines and in vivo models investigating its therapeutic potential.
Product Specifications
CAS Number
52617-37-5
Product Name Alternative
Inhibitor, inhibit, JAK, JAK2, JNK, PARP, HSV, ERK, Akt, Apoptosis, Caspase, Bcl-2, Rubescensine B, ROS, STAT3, STAT, PI3K, Ponicidin
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.98% (May vary between batches)
Solubility
DMSO:242.5 mg/mL (669.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.8 mM)
Smiles
[H][C@]12CC[C@]3 ([H]) [C@]4 (C (=O) C1=C) [C@@]2 ([H]) O[C@@]1 ([H]) O[C@]4 (O) [C@@H] (O) [C@]2 ([H]) C (C) (C) CC[C@H] (O) C312
Molecular Formula
C20H26O6
Molecular Weight
362.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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