Leukadherin-1
Leukadherin-1 is a small molecule allosteric activator of the integrin CD11b/CD18 (Mac-1) . It promotes CD11b-dependent adhesion to ligands like fibrinogen while inhibiting leukocyte migration, making it a valuable research tool for studying inflammation in both cellular and animal models.
Product Specifications
CAS Number
344897-95-6
Product Name Alternative
Endothelium, ICAM-1, Inhibitor, Integrin, Leukadherin 1, Leukadherin1, Leukadherin-1, leukocyte, inhibit, inflammatory, Mac-1, CR3, Complement System, ComplementSystem, CD11b/CD18, adhesion, vascular, αMβ2
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:15 mg/mL (35.59 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) c1ccc (cc1) -c1ccc (\C=C2/SC (=S) N (Cc3ccccc3) C2=O) o1
Molecular Formula
C22H15NO4S2
Molecular Weight
421.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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