JNJ-67856633
JNJ-67856633 is a first-in-class, orally bioavailable, and selective allosteric inhibitor of the MALT1 protease. This small molecule research tool has demonstrated activity in preclinical models, including the induction of tumor stasis in vivo, and is used to investigate MALT1's role in lymphoma and autoimmune disease pathways.
Product Specifications
CAS Number
2230273-76-2
Product Name Alternative
Allosteric, active, orally, JNJ67856633, JNJ-67856633, JNJ 67856633, mucosa associated lymphoid tissue lymphoma translocation gene 1, inhibit, Inhibitor, MALT1, potent, selective
Field of Research
Immunology & Inflammation
Purity
99.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (10.7 mM) ; DMSO:125 mg/mL (267.48 mM)
Smiles
FC (F) (F) c1c (cnn1-c1cccc2c1cc[nH]c2=O) C (=O) Nc1ccnc (c1) C (F) (F) F
Molecular Formula
C20H11F6N5O2
Molecular Weight
467.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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