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JNJ-67856633

JNJ-67856633 is a first-in-class, orally bioavailable, and selective allosteric inhibitor of the MALT1 protease. This small molecule research tool has demonstrated activity in preclinical models, including the induction of tumor stasis in vivo, and is used to investigate MALT1's role in lymphoma and autoimmune disease pathways.

Product Specifications

CAS Number

2230273-76-2

Product Name Alternative

Allosteric, active, orally, JNJ67856633, JNJ-67856633, JNJ 67856633, mucosa associated lymphoid tissue lymphoma translocation gene 1, inhibit, Inhibitor, MALT1, potent, selective

Field of Research

Immunology & Inflammation

Purity

99.87% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (10.7 mM) ; DMSO:125 mg/mL (267.48 mM)

Smiles

FC (F) (F) c1c (cnn1-c1cccc2c1cc[nH]c2=O) C (=O) Nc1ccnc (c1) C (F) (F) F

Molecular Formula

C20H11F6N5O2

Molecular Weight

467.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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