Mollugin

Mollugin (Rubimaillin) is a natural small molecule with research applications as a JAK2 inhibitor, suppressing inflammation via the JAK-STAT and NF-κB pathways. It demonstrates potential in oncology research, including OSCC and HER2-overexpressing cancers, and in bone disorder models by upregulating Nrf2/HO-1. Studies support its use in both in vitro and in vivo experimental contexts.

Product Specifications

CAS Number

55481-88-4

Product Name Alternative

Reactive Oxygen Species, ROS, Rubimaillin, VEGFR, Vascular endothelial growth factor receptor, Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, Mollugin, inhibit, JAK2, Myc, Inhibitor, Liver cancer, Hep3B, HeLa, HEK293, HepG2 cells, HER2, H22-tumor, DNA damage, c-Myc, antitumor, anti-hepatocellular, Apoptosis

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

≥95% (May vary between batches)

Solubility

Chloroform, Dichloromethane, Ethyl Acetate, Acetone:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.03 mM) ; DMSO:31.56 mg/mL (111.01 mM)