TRPC6-PAM-C20
TRPC6-PAM-C20 is a selective positive allosteric modulator of the TRPC6 ion channel. It potentiates OAG-induced platelet aggregation and elevates intracellular calcium in TRPC6-expressing HEK cells with an EC50 of 2.37 μM. This compound is a valuable research tool for studying TRPC6 function in cardiovascular and renal systems in vitro.
Product Specifications
CAS Number
667427-75-0
Product Name Alternative
3- (6,7-Dimethoxy-3,3-dimethyl-3,4-dihydro-isoquinolin-1-yl) -chromen-2-one, TRPVChannel, TRPV Channel, TRPChannel, TRPC6, TRPC6-PAM-C20, TRP Channel
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
90.00% (May vary between batches)
Solubility
DMSO:90 mg/mL (247.65 mM)
Smiles
COc1cc2CC (C) (C) N=C (c2cc1OC) c1cc2ccccc2oc1=O
Molecular Formula
C22H21NO4
Molecular Weight
363.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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