Irigenin
Irigenin is a small molecule that exerts antimetastatic effects by selectively inhibiting α9β1 and α4β1 integrin binding to the Extra Domain A C-C loop. It also sensitizes gastric cancer cells to TRAIL-induced apoptosis in vitro by upregulating pro-apoptotic proteins, highlighting its utility in cancer mechanism and therapy research.
Product Specifications
CAS Number
548-76-5
Product Name Alternative
TRAIL, transition, NF-kB, NFkB, NFκB, NF-κB, metastasis, lung, loop, inhibit, Irigenin, Inhibitor, Integrin, gastric, Epithelial-Mesenchymal, EDA, carcinoma, cancer, apoptosis, C-C
Field of Research
Cell Biology, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM) ; DMSO:65 mg/mL (180.4 mM)
Smiles
COc1cc (cc (O) c1OC) -c1coc2cc (O) c (OC) c (O) c2c1=O
Molecular Formula
C18H16O8
Molecular Weight
360.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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