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SIRT7 inhibitor 97491

The small molecule inhibitor 97491 selectively targets SIRT7 (IC50 = 325 nM), functioning as a specific HDAC inhibitor. It induces apoptosis via caspase activation and is a valuable research tool for studying SIRT7's role in cancer biology and cellular processes in vitro.

Product Specifications

CAS Number

1807758-81-1

Product Name Alternative

Deacetylase, Inhibitor, p53 K373/382, inhibit, Apoptosis, Sirtuin, SIRT7, SIRT7 inhibitor 97491, SIRT-7 inhibitor 97491, tumor

Field of Research

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Purity

99.75% (May vary between batches)

Solubility

DMSO:250 mg/mL (874.95 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (17.5 mM)

Smiles

Nc1cccc (Nc2ncc (o2) -c2ccc (Cl) cc2) c1

Molecular Formula

C15H12ClN3O

Molecular Weight

285.73

Storage Conditions

-20°C

Notes

For research use only.

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