Lotamilast
Lotamilast (RVT-501) is a potent and selective PDE-4 inhibitor with an IC50 of 2.8 nM. It is a research compound investigated for treating inflammatory skin conditions like atopic dermatitis, with studies exploring its anti-inflammatory effects in both cellular and animal models.
Product Specifications
CAS Number
947620-48-6
Product Name Alternative
Inhibit, Lotamilast, PDE4, Inhibitor, E6005, E-6005, E 6005, RVT 501, RVT501, RVT-501, Phosphodiesterase (PDE), phosphodiesterase
Field of Research
Metabolism Research
Purity
97.03% (May vary between batches)
Solubility
DMSO:50 mg/mL (105.82 mM)
Smiles
CNc1nc (-c2cccc (NC (=O) c3ccc (cc3) C (=O) OC) c2) c2cc (OC) c (OC) cc2n1
Molecular Formula
C26H24N4O5
Molecular Weight
472.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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